Mammalian neural cells contain at least two forms of brain spectrin: brain spectrin (240/235) which is located primarily in the axons and presynaptic terminals of neurons, and brain spectrin (240/235E) which is found in the cell bodies, dendrites and postsynaptic terminals of neurones. Brain spectrin (240/235E) is also found in certain glial cell types. Antibodies against red blood cell spectrin detect only brain spectrin (240/235E), while antibodies against brain spectrin isolated from axonal and synaptic membranes detect brain spectrin (240/235). Previous (...) apparent discrepancies in the literature concerning brain spectrin localization at the light microscope level were undoubtedly due to different laboratories detecting distinct brain spectrin subtypes, based on the particular antibody being utilized for immunohistochemistry. In this review we (1) discuss the data supporting the presence of at least two distinct subtypes of mammalian brain spectrin, (2) explain how these results reconcile previous discrepancies concerning the localization of spectrin within neural cells, and (3) suggest the future implications of these findings. (shrink)

Treatise, with commentaries, on Navya-Nyāya philosophy.

Commentary on Raghunātha Śiromaṇi's Tattvacintāmaṇididhiti dealing with minor premise (pakṣatā) according to navya-nyāya point of view.

Classical work with Tarkāmr̥tataraṅgiṇī by Mukundabhaṭṭa, 19th cent. and Caṣaka and Caṣakatātparya by Gaṅgārāmajaḍī, 18th cent., on Nyaya philosophy.

Dictionary of terminology of Yoga philosophy.

Gloss on Raghunathaśiromaṇi's Dīdhiti, commentary on Tattvacintāmaṇi of Gaṅgeśa, basic work on neo-Nyaya school in Hindu philosophy.

Supercommentary on Tattvacintāmaṇidīdhiti, 16th century commentary, by Raghunātha Śiromaṇi on Tattvacintāmaṇi, 13th century basic work of the neo-Nyāya school in Hindu philosophy, by Gaṅgeśa; portion dealing with definition of invariable concomitance (vyāpti).

In a companion review1 we discussed the data supporting the conclusion that at least two subtypes of spectrin exist in mammalian brain. One form is found in the cell bodies, dendrites, and post‐synaptic terminals of neurons (brain spectrin(240/235E)) and the other subtype is located in the axons and presynaptic terminals (brain spectrin(240/235)). Our recent understanding of brain spectrin subtype localization suggests a possible explanation for a conundrum concerning brain 4.1 localization. Amelin, an immunoreactive analogue of red blood cell (rbc) cytoskeletal (...) protein 4.1, is localized in neuronal cell bodies and dendrites when brain sections are stained with antibody against rbc protein 4.1. However, it has recently been suggested that synapsin I, a neuron‐specific phosphoprotein associated with the cytoplasmic surface of small synaptic vesicles, is related to erythrocyte 4.1. In this review we hypothesize that there are at least two forms of brain 4.1: a cell body/dendritic form (amelin) which is detected with rbc protein 4.1 antibody, and a unique form found exclusively in the presynaptic terminal (synapsin I). The binding of synapsin I to brain spectrin(240/235), and its ability to stimulate the spectrin/F‐actin interaction in a phosphorylation‐dependent manner suggests a model for the regulation of synaptic transmission mediated by the neuronal cytoskeleton. (shrink)

This article explores an aspect of women’s transnational labor migration that has been understudied in many labor-sending countries: how men experience shifts in the household labor division triggered by women’s migration. In so doing, we shed light on the diverse ways notions of masculinity and gender identities are being reworked and renegotiated in the transnational family. Drawing on qualitative data collected from in-depth interviews with carers of left-behind children in Northern Vietnam, we show how men are confronted with the need (...) to take on child care duties, which have traditionally been ascribed to women, while at the same time being under considerable pressure to live up to locally accepted masculinity ideals. We provide interesting insights into the changing family structures and dynamics in Vietnamese society where patriarchal norms continue to exert significant influence on different facets of life. (shrink)

Gene therapy approaches have great promise in the treatment of neurodegenerative disorders and malignant brain tumors. Neuwelt et al. review available viral-mediated gene therapy methods and their blood-brain-barrier (BBB) disruption delivery technique, briefly mentioning nonviral mediated gene therapy methods. This commentary discussed the BBB disruption delivery technique, viral and nonviral mediated gene therapy approaches to Parkinson's disease, and the potential use of antisense oligo to suppress malignant brain tumors.

Geiger considers dilettantism as an aesthetic attitude (inner concentration) that undermines the subject's ability to truly perceive the essential value of the artwork and thus calls for outer concentration to actualize the justice of the work itself. Geiger's position suggests that we must pay equitable attention to artworks and that this attitude requires a theory of aesthetic perception -- phenomenological realism. However, the complexity of the aesthetic experience presents Geiger with several challenges, not least of which is the realisation of (...) an attitude that bridges emotion and value in aesthetic experience. This paper will attempt to defend and develop the legitimacy of Geiger's position. First, I will clarify Geiger's critique of dilettantism and suggest how this critique distinguishes him from other aesthetic claims; second, I argue that Geiger argues for an aesthetic attitude that distinguishes everyday emotions and thus ensures the value of the work of art as its own; finally, I will complete Geiger's position by drawing on later phenomenology that answers the question of how we realise the perception of artworks. (shrink)

On concept of god in Hinduism and Hindu philosophy.

On November 4,1999, in South Central Regional Medical Center v. Pickering, 1999 WL 1000703, the Mississippi Supreme Court created a new legal standard that allows patients to recover damages for fear of exposure to AIDS even though they cannot prove actual exposure. By adopting this standard, the Mississippi Supreme Court joined the minority of jurisdictions seeking to encourage providers to use reasonable care when handling instruments capable of transmitting disease.Plaintiff Jimmie Pickering is a female diabetic, who was receiving treatment at (...) South Central Regional Medical Center between September 30 and October 5, 1987 to regulate her blood sugar levels. Pickering used the hospital's Autoclix machine, which required that Pickering use lancets to prick her finger to draw blood. (shrink)

An account of how the mathematical sciences turn the mind away from becoming and towards being. There are four main conclusions. 1. The study of numbers, when treated independently of the other sciences, uses a particular conception of the nature of numbers to detach the mind from the influence of perceptible objects. 2. The study of ratios and proportions, explicitly the core of Plato's harmonics, is fundamental also to plane and solid geometry and astronomy. 3. Ratios and proportion form the (...) basis for the synoptic vision of all the mathematical sciences. This vision is an essential preparation for dialectic because it makes mathematicians become aware of the limitations of the mathematics they have been engaged in but it also shows them how they can begin to overcome those limitations. 4. The main purpose of the study of numbers, treated finally in relation to the other sciences, is to calculate ratios. (shrink)

Since the 1990s, grammatical complexity has received substantial research attention in applied linguistics. The representation of grammatical complexity has expanded in L2 writing with the application of diverse measures in empirical studies in the recent three decades. In response to this situation, we found it important to revisit grammatical complexity, and an exploratory factor analysis was applied to explore latent dimensions of grammatical complexity in L2 writing. We analyzed Lu’s 14 grammatical complexity measures in the L2 corpus of the British (...) Academic Written English Corpus. We then proposed a four-factor model with “clausal subordination,” “phrasal construction”, “global length unit” and “others.” The four factors generally align with the types of grammatical complexity proposed in Lu, but differences on six measures are also found. Noteworthy points were discussed to interpret the reasons behind the differences. Research implications are provided to show further research directions. (shrink)

1 Background for the Uninitiated RICHMOND CAMPBELL Paradoxes are intrinsically fascinating. They are also distinctively ...

Given that care duties are central to the definition of motherhood across contexts, an extended separation from the woman’s family due to migration presents a major threat to her social identity as a mother and wife. Drawing on West and Zimmerman’s notion of “doing gender” and ethnographic research on Vietnamese low-waged contract workers in Taiwan, I provide vital insights into the discursive processes and everyday practices that underlie migrant women’s negotiations of motherhood and femininity. Specifically, I examine the various ways (...) migrant women perform and negotiate meanings of hy sinh and chịu đựng that are core values of Vietnamese womanhood. Combating the stigma of bad motherhood and failed femininity, I emphasize, is not just about reasserting one’s sense of gendered self but also about reassuring her access to the future support and care of the family. The study emphasizes intentionality and pragmatism in women’s social doings of gender and highlights moral dilemmas in gender politics. (shrink)

This article problematizes the way of thinking schooling in discourse of sign system, which involves opposition, and double gesture of inclusion/exclusion. Drawing on two fundamental texts of Taoism, the Tao Te Ching and Chuang Tzu, this article puts forward the seemingly passive Non-Word and Non-Self to resist the hierarchy ordering of conceptions and man, and to undo duality of binary opposition. It links the history of assessment and PISA to the rethinking of evidence and sign in contemporary movements. The second (...) section proposes teaching as wandering (you, 游), the transcendence into Non-Self with response to men’s natural inquiry, but not artificially manipulating and shaping man by privileging certain knowledge, value, and thoughts over other. Instead of making categories of race, gender, and normal/abnormal, Taoist provides a way of reconsider the self operating on assessing, standardizing, normalizing, correcting and predicting others in school accountability. It is built on the ontology of considering individual as belonging to an ultimate sameness, the oneness. The article concludes with underlying assumption that students are subjected to change, and their difference must be eliminated through standard test. It further questions tactics of reason that educational reform face in the current regime of school accountability. (shrink)

The Confucian classic the Liji 禮記 defines ‘desire’ as ‘the arousal of nature’. In line with this classical definition, Dai Zhen 戴震 sees desire as human nature in activation. However, while the Liji ascribes human deceits and debauchery to the susceptibility of human nature, Dai Zhen speaks highly of its responsiveness and receptivity. This article discusses Dai Zhen’s conception of desire and argues that Dai Zhen distinguishes himself from other Confucian moral thinkers by bringing to light the dimension of the (...) Other in addressing the issue of desire. As the Confucian tradition has long been disturbed by an anxiety to keep desire in check, Dai Zhen draws our attention to how to cultivate the affective faculty inherent in human nature to develop our sensitivity to the needs and desires of others, especially those of the widow, the orphan, the solitary, the sick, and the weak. (shrink)

This study examines values and value types as well as scores in levels of moral reasoning for␣students enrolled in a business program. These two factors are measured using the Schwartz Personal Values␣Questionnaire and the Defining Issues Test 2. No statistically significant differences in levels of moral␣reasoning, rankings of values, and value types could be attributed to gender. However, eight significant correlations between value types and levels of moral reasoning provide evidence that a systematic relationship exists. The relationships are not only (...) internally consistent but also consistent with the model of values based on motivational goals (Schwartz S. H. and K. Boenke: 2004, Journal of Research in Personality, 38 230–255). (shrink)

Whether nature is valuable on its own (intrinsic values) or because of the benefits it provides to humans (instrumental values) has been a long-standing debate. The concept of relational values has been proposed as a solution to this supposed dichotomy, but the empirical validation of its intuitiveness remains limited. We experimentally assessed whether intrinsic/relational values of sentient beings/non-sentient beings/ecosystems better explain people’s sense of moral duty towards global nature conservation for the future. Participants from a representative sample of the population (...) of Singapore (n = 1508) were randomly allocated to two “the last human” scenarios. We found that the best predictor of such a sense of moral duty for future nature conservation is the recognition of the intrinsic values of sentient beings. Our results suggest that the concern for animal welfare may enhance rather than compete with the sense of moral duty towards nature conservation. (shrink)

Abstrak: John Zizioulas merefleksikan kembali doktrin Allah Trinitaris dan mencoba mencari cara-cara baru menolong umat beriman zaman ini menemukan makna ajaran iman ini. Merujuk teologi para Bapa Gereja Kapadokia, Zizioulas mengajukan gambar Allah Trinitaris sebagai Pribadi yang berkomunitas. Pribadi memiliki tiga karakteristik: primer dan absolut, ekstasis dan hipostasis, unik dan tak tergantikan. Pribadi selalu bergerak ke luar dirinya, ke arah pribadi yang lain, maka ia menerima keberbedaan. Kehidupan dan identitas otentik pribadi ditemukan hanya di dalam komunitas yang dibangunnya bersama pribadi-pribadi (...) yang lain. Gerak Pribadi Allah adalah eros, cinta yang merangkul pribadi-pribadi yang lain beserta keberbedaan mereka, yakni manusia dan segenap ciptaan. Berkomunitas dengan Allah dan segenap ciptaan, manusia melampaui substansi manusiawi dan kondisi naturalnya. Manusia tidak lagi menjadi milik kematian melainkan kehidupan kekal. Gereja adalah image Allah Trinitaris karena ia adalah komunitas pribadi-pribadi yang mengalami kelahiran baru oleh Roh Kudus di dalam peristiwa Kristus. Sebagai image Allah Trinitaris, cara Gereja hadir di dunia ialah dengan menjadi komunitas katolik dan ekaristis. Untuk menjadi komunitas katolik-ekaristis, pembaruan cara hidup, struktur hirarkis, dan pelayanan Gereja adalah sebuah kebutuhan. Kata-kata Kunci: pribadi, substansi, ekstasis-hipostasis, keberbedaan, identitas otentik, komunitas ekaristis, imago Dei/Trinitatis, eros. Abstract: John Zizioulas did his reflection on the doctrine of the Trinity in term to seek new ways that help the faithful to grasp the meaning of this teaching. Referring to the theology of Cappadocian Fathers, Zizioulas provides a picture of the Trinity as Persons within communion. A person has three primary characteristics: primary and absolute, ecstatic and hypostatic, unique and irreplaceable. A person always moves towards others, thus she/he embraces otherness. The very life and authentic identity of a person can be found only in communion with others. The Person of God moves as eros, God’s love which embraces the others and otherness, i.e. human beings and the rest of creation. Being in communion with God and all creations, human being overcomes the human substance and its nature. Human being no longer belongs to death but to eternal life. The church is an image of the Trinity for it is a communion of the new persons that were delivered by the Holy Spirit within the Christ event. As the image of the Trinity, the Church’s way of being in this world is by becoming a catholic and eucharistic community. To be such a community, the renewal of the Church’s way of life, hierarchical structure, and ministries is a necessity. Kata-kata Kunci: Person, substance, ecstatic-hypostatic, otherness, authentic identity, eucharistic community, image of God/image of the Trinity, eros. (shrink)

This book is an analysis of a selection of Adorno s work distinguishing his dialectics from Hegel, Marx and other members of the Frankfurt School (Benjamin, Kracauer, Marcuse) in the analysis of jazz, popular music, radio and pre-war pro-fascist propaganda.".

Learning disabilities are highly prevalent on college campuses, yet students with learning disabilities graduate at lower rates than those without disabilities. Academic and psychosocial supports are essential for overcoming challenges and for improving postsecondary educational opportunities for students with learning disabilities. A holistic, multi-level model of campus-based supports was established to facilitate culture and practice changes at the institutional level, while concurrently bolstering mentors’ abilities to provide learning disability-knowledgeable support, and simultaneously creating opportunities for students’ personal and interpersonal development. Mixed (...) methods were used to investigate implementation of coordinated personal, interpersonal, and institutional level supports for undergraduate science, technology, engineering, and math (STEM) students with learning disabilities. A one-group pre-test post-test strategy was used to examine undergraduate outcomes. Participants included 52 STEM undergraduates with learning disabilities, 57 STEM graduate student mentors, 34 STEM faculty mentors, and 34 university administrators and personnel as members of a university-wide council. Enrolled for two years, undergraduates were engaged in group meetings involving psychoeducation and reflective discussions, development of self-advocacy projects, and individual mentorship. Undergraduates reported improved self efficacy (p =.001), campus connection (p <.001), professional development (p ≤.002), and self advocacy (p <.001) after two academic years. Graduate student mentors increased their understanding about learning disabilities and used their understanding to support both their mentees and other students they worked with. Council members identified and created opportunities for delivering learning disability-related trainings to faculty, mentors and advisors on campus, and for enhancing coordination of student services related to learning and related disorders. Disability-focused activities became integrated in broader campus activities regarding diversity. This research explicates a role that college campuses can play in fostering the wellbeing and the academic and career development of its students with developmental learning and related disorders. It offers an empirically tested campus-based model that is multilevel, holistic, and strengths-based for supporting positive outcomes of young people with learning disabilities in STEM. Moreover, findings advance the knowledge of supports and skills that are important for self-regulating and navigating complex and multi-faceted disability-related challenges within both the post-secondary educational environment and the young adults’ sociocultural context. (shrink)

This article examines the complexity of feminized domestic labor in the context of global migration. I view unpaid household labor and paid domestic work not as dichotomous categories but as structural continuities across the public and private spheres. Based on a qualitative study of Filipina migrant domestic workers in Taiwan, I demonstrate how women travel through the maid/madam boundary—housewives in home countries become breadwinners by doing domestic work overseas, and foreign maids turn into foreign brides. While migrant women sell their (...) domestic labor in the market, they remain burdened with gendered responsibilities in their own families. Their simultaneous occupancy of paid and unpaid domestic labor is segmented into distinct spatial settings. I underscore women’s agency by presenting how they articulate their paid and unpaid domestic labor and bargain with the monetary and emotional value of their labor. (shrink)

Following Smaldino's definition, we claim that language is also an emergent group-level trait, and propose two facets to verify this statement, both of which also provide a general framework to address the future work about group-level traits.

The discourses of Antillanité and Créolité are both based on the absence of women. This is more important in the discourse of Créolité since it silences the grandmothers, great aunts and village midwives who are the transmitters of folk tales, folk medicines and oral culture. In the struggle for recognition between Caribbean males and western males folk medicine may be too closely associated with the denigrated female role to be considered a suitable inclusion into modern development.

După un sfert de veac -- Pelerinaj oriental: Ex oriente lux? ; Fascinația yogii -- Pelerinaj occidental: O yogă europeană ; Ucenicie întru ale cugetării -- Pelerinaj românesc: Popasuri la compatrioți -- Pelerinaj muzical și inițiatic: Călătoria în noi înșine ; Realitatea interioră ; Chemarea transcendenței ; Forța care dă viață ; Ideea de inițiere ; Profanatorii misterelor ; Marea ascensiune -- Pelerinaj lăuntric: Ce este spiritul?

Mental health is a kind of emotional state, a good psychological state can have a positive impact on a person, physical exercise can have a positive impact on the psychological state of college students, prevent the generation of negative emotions, improve the bad emotional state, and then promote the mental health of college students. Health is an inevitable requirement to promote the all-round development of people and a basic condition for economic and social development. Health education should be incorporated into (...) the national education system to promote the national health of the people through sports. Young people are the main force and backbone of national and social development. In order to realize the Chinese dream of great rejuvenation, we must attach importance to the development of young people and the physical and mental health of young people. In the process of compulsory education, middle school and high school period is a key stage in the gradual formation and development of students' psychology and body, but due to the large audience of China's education, the competition is more intense, which inevitably causes a lot of students to focus on exam-oriented education and neglect physical health, especially in recent years, the mental health issues of increasing concern. Through the research situation of mental health in China and the concept of mental health quality, this paper analyzes the problems of sports and mental health, and puts forward some corresponding suggestions for the problems, which has reference significance for promoting students' mental health. (shrink)